The AI CEO Podcast with Seema Alexander
A podcast for CEOs and executives on rewiring business strategy and operations for the artificial intelligence era, avoiding hype and jargon.
This is a strategic interview show for senior business leaders, not technologists. It bypasses entry-level AI discussions about productivity tools, focusing instead on the second-order effects of AI: collapsing team structures, the nature of trust and reality, and building new competitive advantages. The conversations are with high-level operators who are implementing AI at scale, providing a framework for CEOs to rethink, reimagine, and rewire their entire organization.
“Unlike many AI podcasts focused on tools or technical details, The AI CEO Podcast maintains a strict C-suite perspective. Its central theme is 'business rewiring'—a fundamental redesign of strategy and operations—which gives it a more urgent and strategic tone than its peers.”
Who hosts this show
Seema Alexander is an AI business futurist, keynote speaker, and the founder of the AI strategy firm Disruptive AI. A former Fortune 500 executive with over two decades of experience in growth strategy and brand repositioning, she now advises CEOs on navigating the AI shift. Through her podcast and advisory work, she focuses on moving leaders from being 'AI-curious' to 'AI-powered' by fundamentally rewiring their business models.
Credentials & credits
- CEO & Founder, Disruptive AI
- MBA, Fordham University (Magna Cum Laude)
- Former Fortune 500 executive (Prudentia Financial)
- Former Co-chair, DC Startup & Tech Week
- Founding Member, Futurist Council for AI and the Future of Work with JFF Labs
- Co-Founder, Virgent AI
Other ventures
- Disruptive AI (AI strategy and implementation studio)
- AI BusinessCon (Business rewiring conference)
- Virgent AI (AI development firm)
- International Keynote Speaker
- Board Member, Codespa America
What kind of podcast
- Country
- United States
- Region
- usa
When new episodes drop
- 01The Mistake Every Leader Is Making Right Now #AI #BusinessJun 23, 2026 · 51s
- 02Why Companies Are Firing Half Their Staff for AI #AI #WorkJun 22, 2026 · 51s
- 03Elon Musk's Trick to Find Real Expertise #businessstrategy #innovationJun 20, 2026 · 2 min
- 04China Already Has This on Every American #databreach #identity #securityJun 18, 2026 · 1 min
- 05Blake Hall WARNS: “We’re Losing Our Grip On Reality” | The AI CEO PodcastJun 17, 2026 · 1h 25m
- 06Former FDA Regulator & Pharma AI Exec REVEALS: “Patients Trust AI More Than Doctors”May 19, 2026 · 1h 11m
Notable episodes
- 01Blake Hall WARNS: “We’re Losing Our Grip On Reality” | The AI CEO Podcast
A deep dive into the societal and business implications of AI on trust and identity, featuring the CEO of a major digital identity company.
- 02Former FDA Regulator & Pharma AI Exec REVEALS: “Patients Trust AI More Than Doctors”
Explores the high-stakes world of AI in healthcare and regulation with a former FDA expert and pharma executive.
- 03Elon Musk's Trick to Find Real Expertise #businessstrategy #innovation
A viral, practical clip sharing a specific hiring tactic from Elon Musk, which reflects the show's focus on actionable insights from top entrepreneurs.
What you'll be asked on this show
The podcast is a long-form interview format hosted by Seema Alexander. She facilitates in-depth conversations with a single guest, often a fellow CEO or industry expert. The production includes on-screen branding, text overlays with a distinct teal glow, and clear outro cards directing listeners to other platforms.
Questions the host keeps coming back to
- “How do you find the people to run these companies?”
Signature segments
- · 'THE AI CEO' logo branding
- · Text overlays with a teal glow effect
- · Outro card with YouTube, Spotify, and Apple Podcasts logos
Topics covered repeatedly
Who gets booked here
Guests are typically founders and CEOs of major tech companies (like ID.me) or senior executives from large enterprises (like AstraZeneca) who are on the front lines of AI implementation. They are chosen for their practical experience in navigating complex issues like regulation, digital identity, and large-scale business transformation.
- Blake Hallon Blake Hall WARNS: “We’re Losing Our Grip On Reality” | The AI CEO Podcast
- Kausar Riaz Ahmedon Former FDA Regulator & Pharma AI Exec REVEALS: “Patients Trust AI More Than Doctors”
Where to find this show
Audience & reach
Sponsors can reach a highly-targeted, influential audience of senior business decision-makers (CEOs, founders, execs) actively seeking solutions for AI strategy and implementation. The value proposition is direct access to leaders with significant purchasing power who are looking to invest in long-term, strategic AI initiatives.
Subscriber and view counts are pulled live from YouTube and re-verified on a 30-day cycle. Listener estimates for the RSS feed aren't published here unless they're host-verified.
Pitch this show
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People also ask
- What is the host's real name?
- The host's name is Seema Alexander.
- Is The AI CEO Podcast still active?
- Yes, the podcast releases new episodes bi-weekly, as of late June 2026.
- What is the format of the show?
- It is a long-form interview podcast where host Seema Alexander speaks with a single guest, typically a CEO, founder, or senior executive, about AI strategy.
- Who is the podcast for?
- The podcast is specifically for CEOs, founders, and business executives seeking strategic insights on implementing AI, rather than technical details.
- How can I pitch a guest for the podcast?
- The podcast description lists [email — gated] for guest and sponsor inquiries.
- Where can I listen to the podcast?
- The podcast is available on YouTube, Spotify, and Apple Podcasts.
Built from the show's public RSS feed, YouTube, the host's own websites, and the cited sources below. Computed and AI-extracted fields are labelled. Facts only — no private info, no fabrication, no transcripts republished.
Sources & how this page was built
This page is AI-assisted, grounded in the public sources cited below, and host-verifiable. We publish facts only; we do not republish transcripts. If anything here is wrong, the host can claim and correct the page above.Model: gemini-2.5-pro · high confidence
- [01]Seema Alexander Official Websiteseemaalexander.com
- [02]Disruptive AI Official Websitegetdisruptive.ai
- [03]AI BusinessCon Official Websitebusinesscon.ai
- [04]Seema Alexander Bio - DC Startup Week 2019dcstartupweek2019.sched.com
- [05]Seema Alexander LinkedIn Profilelinkedin.com
- [06]The AI CEO Podcast - YouTube Channelyoutube.com
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